Arthritis is an extremely common condition that develops in the knee over time most often due to wear and tear on the knee joint. Arthritis results in a loss of articular cartilage, the gliding surface of the knee. This results in a progressive roughening of the surfaces within the knee. Pain and swelling results, especially with increased activity.
There are three compartments in the knee. Medial (inner) and lateral (outer) compartments serve as the articulation between femur (thigh bone) and tibia (leg bone). The patello-femoral compartment is in the front of the knee. Arthritis is classified based on severity (amount of cartilage damage and joint space narrowing) as well as which compartments are involved. Tricompartmental arthritis is treated surgically with a total knee replacement. Arthritis that is localized only to the inner (medial) compartment of the knee can be treated with a unicompartmental knee replacement. This type of knee replacement replaces only the damaged compartment of the knee while preserving the lateral and patellofemoral compartments of the knee that have normal cartilage.
There are many cases of arthritis that can be managed with conservative measures. These conservative measures include, rest, icing, NSAIDs (anti-inflammatories), physical therapy, bracing, assistive devices, and activity modification. When these measures fail to control pain and the patient is unsatisfied with the quality of life allowed by the knee, surgery can be an effective treatment for the pain associate with arthritis.
The following case example demonstrates a patient with isolated medial compartment arthritis that was treated with a unicompartmental knee replacement (Figure 1.)

Figure 1. a. The right knee has narrowing of the joint space between the femur and tibia only on the inner compartment of the knee. The left knee has normal cartilage and no joint space narrowing. b. The patellofemoral joint has normal cartilage. c. The right knee has undergone a unicompartmental knee replacement restoring alignment to the knee and relieving pain.
Several criteria must be met for unicompartmental knee replacement to be effective and successful:
When these criteria or met, a unicompartmental knee replacement is a very good option. If any of the criteria are not met, a total knee replacement is a safer option.
If a patient has isolated arthritis in the medial compartment and has tried all conservative measures to control pain, a unicompartmental knee replacement is an effective option to relieve pain and improve function. Prior to undergoing a knee replacement procedure, one must have exhausted all conservative options and must be in severe pain. All surgery that involves artificial components has the risks of loosening, hardware failure, infection, mal-position of components, stiffness, injury to nerves and vessels, and scar tissue formation. The surgery has the risks of bleeding, blood clot formation, and other severe medical complications. Fortunately these risks are very rare but the risk of surgery must be weighed against the severity of the pain and disability of the knee.
Long term studies document 90-95% well functioning prostheses at 15 years. Unicompartmental knee replacements that loosen or fail are converted to total knee replacements.